Bedtime Aspirin may reduce acute heart events - heart attack or stroke!!


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In my previous post I covered ''Aspirin'' therapy recommended by doctors for the people at the risk of stroke or heart attack. This practice has been  common in western counties for more than three decades, particularly in the US. As mentioned in the post, it is not recommended for people who  have stomach ulcer problems and other medical disorders. Though latest studies come-up with different views and the benefit of aspirin therapy - daily dosage for senior citizens is still a subject of debate and a common consensus is not yet arrived.
 Way back in 2013 an interesting research on the positive effects of aspirin was done by a group of doctors at a Netherlands hospital and it was  presented at the American Heart Association's Scientific Sessions 2013.   According to this well-researched study, taking aspirin at bedtime instead of in the morning might reduce acute heart events. The study recommended  low-dose daily aspirin  for people at high risk of heart disease and for reducing the risk of recurrent heart events. As you may be aware and is proven medically that Aspirin thins the blood and makes it less likely to clot. Further, it is mentioned that the  tendency for platelets (blood's clotting cells) activity is found to be higher  in the morning.
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 The Aspirin in Reduction of Tension II trial is the first unique study to explore the timing of aspirin intake among cardiovascular disease patients. A randomized, open-label study was done on  290 patients who took either 100 mg of aspirin upon waking or at bedtime during two 3-month periods. At the end of each period, blood pressure and platelet activity was measured to understand the impact of aspirin intake on blood and clotting. It was found out that blood pressure was not reduced; however, bedtime aspirin platelet activity was reduced by 22 units in the case of a group that took aspirin as recommended by the researchers. 
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 "Because higher platelet activity contributes to a higher risk of acute heart events, this simple intervention just  switching aspirin intake from morning to bedtime  could be beneficial for the millions of patients with heart disease who take aspirin on a daily basis," said Tobias Bonten, M.D., Ph.D student at the Leiden University Medical Center in the Netherlands (Nov. 13, 1013).

If you think of ''Aspirin'' therapy to reduce heart events in the future, it is a must to consult your cardiologist or family doctor because the major side effect of aspirin is it may aggravate internal stomach bleeding in the case of ulcer patients.
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The above story is based on materials provided by American Heart Association.